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ea0081ep751 | Pituitary and Neuroendocrinology | ECE2022

Immunohistochemichal expression of ephrin receptor (EPH)-A4, -A5, -B2 and -B5 in pituitary lesions

Papadimitriou Eirini , Kyriakopoulos Georgios , Barkas Konstantinos , Gkalonakis Ioannis , Pantoula Panagiota , Theocharis Stamatios , Kaltsas Gregory , Alexandraki Krystallenia

Introduction: Ephrin receptors (EPHs) compose the largest known subfamily of receptors tyrosine kinases and are bound and interact with EPHs-interacting proteins (Ephrins). They have a role in tumor growth, invasion, angiogenesis and metastasis of several neoplasms. Aim of the study was to investigate the expression of EPH-A4, -A5, -B2 and -B5 in pituitary lesions. Material and Methods: Our study group consisted of 18 patients (9 males with median age 54...

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ea0063p873 | Adrenal and Neuroendocrine Tumours 3 | ECE2019

Immunohistochemical expression of ephrines A2 and A4 receptors in neuroendocrine neoplasms: preliminary results

Alexandraki Krystallenia , Antonopoulou Ioanna , Karaflou Maria , Christakou Charikleia , Mavroeidi Vasiliki , Karapanagioti Aggeliki , Lekkakou Maria , Anagnostou Elli , Tsoli Marina , Angelousi Anna , Delladetsima Ioanna Kassiani , Felekouras Evangelos , Sotiropoulos Georgios , Kaltsas Gregory , Theocharis Stamatios

Introduction: Ephrin receptors (EPHs) have a role in tumor growth, invasion, angiogenesis and metastasis of several neoplasms. Aim of the study was to investigate the expression and possible clinical significance of EPH-A4 and EPH-A2 protein expression in the pathophysiology of neuroendocrine neoplasms (NENs).Methods: EPH-A4 and -A2 protein expression was assessed by immunohistochemical analysis along with Ki-67 proliferation index (%) on 28 paraffin emb...

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Endocrine Abstracts

Immunohistochemichal expression of ephrin receptor (EPH)-A4, -A5, -B2 and -B5 in pituitary lesions

Immunohistochemical expression of ephrines A2 and A4 receptors in neuroendocrine neoplasms: preliminary results

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